Research Center for Advanced Science and Technology (RCAST), the University of Tokyo is making a study of various fields cross sectionally under the four principles; interdisciplinarity, fluidity, internationality, and openness since its establishment. Among this group, LSBM (Laboratories for Systems Biology and Medicine) is a virtual aggregate of more than 10 laboratories which synergistically explore the frontier of life science. Their research field ranges from cancer science, metabolic medicine, -omics analysis, structural biology, biological measurement, data and computational science, and automation, in order to find a new “sapience” in biomedical science and offer its values to the world.